Attracting Startups within Creative Industries and the High-Tech Sector. An Analysis of Location Factors from the Stakeholders’ Perspectives

The article focuses on startups within creative industries and the high-tech sector (the so-called TIME sector) and the relevance of the factors affecting the location choice of startups within these newly emerging industries. In terms of building a prospering startup ecosystem, results of this empirical research provide recommendations for representatives and designers in charge of destination management and regional development. For founders and entrepreneurs, the research will define which factors are relevant for their location choice. The article argues that the perspectives of stakeholders (entrepreneurs / startups and external experts) differ in some ways on the relevance of certain location factors. It also argues that the main challenge for destination management and regional development will be the dilemma between a generally positive economic situation and the development of a prosperous startup ecosystem

Attracting Startups within Creative Industries and the High-Tech Sector. An Analysis of Location Factors from the Stakeholders’ Perspectives

The article focuses on startups within creative industries and the high-tech sector (the so-called TIME sector) and the relevance of the factors affecting the location choice of startups within these newly emerging industries. In terms of building a prospering startup ecosystem, results of this empirical research provide recommendations for representatives and designers in charge of destination management and regional development. For founders and entrepreneurs, the research will define which factors are relevant for their location choice. The article argues that the perspectives of stakeholders (entrepreneurs / startups and external experts) differ in some ways on the relevance of certain location factors. It also argues that the main challenge for destination management and regional development will be the dilemma between a generally positive economic situation and the development of a prosperous startup ecosystem

Einsatzgebiete und Anwendungsfälle von Künstlicher Intelligenz in der Wertschöpfungskette der zehn größten Medienunternehmen Deutschlands

Künstliche Intelligenz (KI) hat sich in den letzten Jahren zu einer der bedeutendsten Technologien entwickelt. Angesichts der symbiotischen Verbindung zwischen Medienbranche und technologischem Fortschritt sowie dessen weitreichenden Auswirkungen insbesondere auf die Wertschöpfungskette, hat dieser Beitrag das Ziel, den Einsatz von KI und deren Anwendungen im Rahmen der Wertschöpfungsketten der zehn größten deutschen Medienunternehmen zu betrachten. Fasst man die wichtigsten Erkenntnisse zusammen, so sind im Untersuchungszeitraum die Wertschöpfungsstufen Beschaffung von Inhalten sowie Distribution die Wertschöpfungsstufen, die in den untersuchten Medienunternehmen am stärksten von KI betroffen sind. Die häufigsten Anwendungsfälle sind Vorlesefunktionen, Sprachassistenten und Chatbots (als Teil der Wertschöpfungsstufe Distribution). Natural Language Processing sowie Sprachassistenten und Speech Recognition sind die KI-Technologien, die insgesamt in den untersuchten Unternehmen zum Untersuchungszeitpunkt am häufigsten eingesetzt werden. ProSiebenSat.1, Bertelsmann, Axel Springer sowie ARD sind die Unternehmen, die im Untersuchungszeitraum hinsichtlich KI-Einsatz am bereitesten aufgestellt sind - breit sowohl hinsichtlich der betroffenen Wertschöpfungsstufen, als auch hinsichtlich der Vielfalt an unterschiedlichen eingesetzten KI-Technologien.Artificial Intelligence (AI) has become one of the most important technologies in recent years. Given the symbiotic relationship between the media industry and technological progress and its far- reaching impact on the value chain in particular, this paper aims to look at the use of AI and its applications in the value chains of the ten largest German media companies. Summarizing the most important findings, the value creation stages of content procurement and distribution are the stages most affected by AI in the media companies studied during the period under review. The most common use cases are read-aloud functions, voice assistants and chatbots (as part of the distribution value chain). Natural Language Processing as well as Speech Assistants and Speech Recognition are the AI technologies that are most frequently used overall in the companies studied at the time of the study. ProSiebenSat.1, Bertelsmann, Axel Springer and ARD are the companies that are most prepared to use AI in the period under review - broadly speaking, both in terms of the value creation stages involved and in terms of the variety of different AI technologies used

Welche Sektoren? Welche Technologien? Welche Regionen? Eine deskriptive Analyse der Technikadaption von jungen Medienunternehmen

Technische Innovationen haben schon immer Medieninnovationen ausgelöst und die Art und Weise der Medienproduktion und Medienvermarktung sowie der Medienrezeption verändert (u.a. Broich 2015: 238; Hasenpusch 2018: 21). Für Medienunternehmen bietet Technik die Möglichkeit zur Differenzierung und das Potenzial, darüber einen Wettbewerbsvorteil für ihre Geschäfts- und Wertschöpfungsmodelle zu generieren. Entsprechend dieser Perspektive dient Technik für Medienunternehmen als Treibergröße und 'enabler' für dauerhaft werthaltige Wettbewerbspositionen (Zerdick et al. 2001; Godefroid/Kühnle 2018). Insofern bearbeitet der vorliegende Beitrag die Frage: Wie gehen insbesondere junge Medienunternehmen mit technologischen Innovationen um und wie adaptieren sie diese? Dabei unterstellt unser theoretischer Bezugsrahmen, dass die Kombination aus Konvergenzmöglichkeiten einer digitalen Medienwirtschaft, den Besonderheiten kreativwirtschaftlicher Güter und regionaler Gegebenheiten Technikadaption spezifisch fördern. Im Ergebnis zeigt sich: Die Technikadaption von Medienunternehmen unterscheidet sich kaum von Unternehmen anderer Sektoren - das heißt Konvergenz- und Kreativitätsguterwartungen bestätigen sich nicht. Aber: Regionale Cluster sind erkennbar

Simple Questionnaires to Improve Pooling Strategies for SARS-CoV-2 Laboratory Testing

Background: Liberal PCR testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is key to contain the coronavirus disease 2019 (COVID-19) pandemic. Combined multi-sample testing in pools instead of single tests might enhance laboratory capacity and reduce costs, especially in low- and middle-income countries. Objective: The purpose of our study was to assess the value of a simple questionnaire to guide and further improve pooling strategies for SARS-CoV-2 laboratory testing. Methods: Pharyngeal swabs for SARS-CoV-2 testing were obtained from healthcare and police staff, hospital inpatients, and nursing home residents in the southwestern part of Germany. We designed a simple questionnaire, which included questions pertaining to a suggestive clinical symptomatology, recent travel history, and contact with confirmed cases to stratify an individual’s pre-test probability of having contracted COVID-19. The questionnaire was adapted repeatedly in face of the unfolding pandemic in response to the evolving epidemiology and observed clinical symptomatology. Based on the response patterns, samples were either tested individually or in multi-sample pools. We compared the pool positivity rate and the number of total PCR tests required to obtain individual results between this questionnaire-based pooling strategy and randomly assembled pools. Findings: Between March 11 and July 5, 2020, we processed 25,978 samples using random pooling (n = 6,012; 23.1%) or questionnaire-based pooling (n = 19,966; 76.9%). The overall prevalence of SARS-CoV-2 was 0.9% (n = 238). Pool positivity (14.6% vs. 1.2%) and individual SARS-CoV-2 prevalence (3.4% vs. 0.1%) were higher in the random pooling group than in the questionnaire group. The average number of PCR tests needed to obtain the individual result for one participant was 0.27 tests in the random pooling group, as compared to 0.09 in the questionnaire-based pooling group, leading to a laboratory capacity increase of 73% and 91%, respectively, as compared to single PCR testing. Conclusions: Strategies that combine pool testing with a questionnaire-based risk stratification can increase laboratory testing capacities for COVID-19 and might be important tools, particularly in resource-constrained settings

Risk governance in organizations

Dieses Buch dokumentiert 10 Jahre Risk-Governance-Forschung an der Universität Siegen. In 50 Beiträgen reflektieren Forscher und Praktiker Risk Governance vor dem Hintergrund ihrer eigenen Forschungen und/oder Erfahrungen und geben jeweils einen Entwicklungsimpuls für die Zukunft der Risk Governance. Das Buch zeigt die große Bandbreite und Tiefe des Forschungsgebietes auf und diskutiert Grundannahmen, Implementierungsfragen, die Rolle der Risk Governance als Transformationsmotor, ihre Wirkung in den verschiedenen betrieblichen Funktionen, Entwicklungsperspektiven und den Beitrag der Risk Governance zu einer nachhaltigen Ausrichtung von Unternehmen.This book documents 10 years of risk governance research at the University of Siegen. In 50 contributions, researchers and practitioners reflect on risk governance against the background of their own research and/or experience and provide a development impetus for the future of risk governance. The book shows the wide range and depth of the research field and discusses basic assumptions, implementation issues, the role of risk governance as transformation engine, its impact in the various operational functions, development perspectives, and the contribution of risk governance to a sustainable orientation of companies

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

International Media Management Insights

The idea is quite obvious. Anyone studying “Media Creation & Management” as part of an international minor program should not just learn about international management topics and international media markets in theory, but also engage in their own media project as part of an international team of students – in this particular case, writing and editing as well as layout and production of a magazine on the topic of international media management. This is exactly what 50 students of the International Media Management class did during the winter term 2022/2023. And the result is the magazine you are now holding in your hands. The students looked at topics related to international media management from various perspectives, analyzed markets and dealt with international digital and media companies – sometimes using management tools, sometimes in a more scientific and sometimes in an entertaining way. The result is a magazine that is directed at students as well as lecturers and those responsible for international exchange programs at universities. Did the students catch your interest? You can find more information about the minor program “Media Creation & Management” at Stuttgart Media University (Hochschule der Medien) and the idea of studying in Stuttgart in this magazine or oline with the top QR-Code on the left. Kind regards and see you in Stuttgart. Yours Uwe Eisenbeis Prof. Dr. Uwe Eisenbeis Dean of Studies, Program Media Managemen

International Media Management Insights

The idea is quite obvious. Anyone studying “Media Creation & Management” as part of an international minor program should not just learn about international management topics and international media markets in theory, but also engage in their own media project as part of an international team of students – in this particular case, writing and editing as well as layout and production of a magazine on the topic of international media management. This is exactly what 50 students of the International Media Management class did during the summer term 2022. And the result is the magazine you are now holding in your hands. The students looked at topics related to international media management from various perspectives, analyzed markets and dealt with international digital and media companies – sometimes using management tools, sometimes in a more scientifi c and sometimes in an entertaining way. The result is a magazine that is directed at students as well as lecturers and those responsible for international exchange programs at universities. Did the students catch your interest? You can fi nd more information about the minor program “Media Creation & Management” at Stuttgart Media University (Hochschule der Medien) and the idea of studying in Stuttgart in this magazine or oline with the top QRCode on the left. Kind regards and see you in Stuttgart. Yours Uwe Eisenbei

International Media Management Insights

The idea ist quite obvious. Anyone studying „Media Creation & Management“ as part of an international minor program should not just learn about international management topics and international media markets in theory, but also engage in their own media project as part of an international team of students – in this particular case, writing and editing as well as layout and production of a magazine on the topic of international media management. This is exactly what 39 students of the International Media Management class did during the summer term 2023. And the result is the magazine you are now holding in your hands. The students looked at topics related to international media management from various perspectives, analyzed markets and dealt with international digital and media companies – sometimes using management tools, sometimes in a more scientific and sometimes in an entertaining way. The result is a magazine that is directed at students as well as lectures and those responsible for international exchange programs at universities. Did the students catch your interest? You can find more information about the minor program “Media Creation & Management” at Stuttgart Media University (Hochschule der Medien) and the idea of studying in Stuttgart in this magazine